DPCstruct | MC24684

Metacluster Properties and Pfam Annotations

Number of structural domains5
Mean domain length (aa)118 ± 8 aa
Standard deviation of domain lengths7.88
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score78.16
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)53.03
Pfam Score100.00
Assigned Pfam label(s) CL0023

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A287N2I5 2-114 VAVGDVIYIEANSGAVKRVGRCDAFATEYDLEAEEYVPIPKGEVHKKKEIVQDVTLHDLDAANAQPQGGQDILSLMGQMMKPRKTEI…
A0A2H3DNP1 1-132 MKTGILTITSIDMEIIYDLGTRMIYALSTENVLASGKITKLGRSFIRSRDYDAMGTNTEFVQCPEGETQQRRKVVHTVFSHEIDVIN…
A0A453DU93 1-122 None
A0A7J9LDG1 1-113 None
A0A6A4X2W1 6-116 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.