DPCstruct | MC24666

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)80 ± 12 aa
Standard deviation of domain lengths12.18
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score91.93
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)30.07
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R8NPN2 1-80 MVNVEPIIINNYTFIAVSVKLPKTNLLAVMSDKGYIMCGALDVGLLNEKLGDRGIIAGRAVGVRTIEQLLEAPLESVTIE
A0A137SJR7 3-83 AKMIRYELEKPLLIIKEKQGMLACAYINVETCNKTNEACAIVSGVSSYEDMMSAKIIAVSNKALNLGVNVGDTGMSAINRF
J1L0E8 71-155 None
A0A523ZL89 11-86 None
A0A523ST13 14-96 None
A0A1V6DU75 110-195 None
A0A843CZT9 25-104 None
A0A150L2P7 2-55 None
A0A7V3FYM9 2-72 None
A0A7S0HII3 3-83 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.