DPCstruct | MC24664

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)532 ± 38 aa
Standard deviation of domain lengths38.48
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score80.24
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)19.46
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A512ISD5 2-520 NVKDRGAKGDGATDDSAALVSADAYAAANGYRYLYFPPGLYYAPAIGQGGKGLSRTILVGEGRLTGASYRQVTPLTGGTTPPPSTDL…
A0A2N2DYI0 220-755 VASKYGVDSTIGTSDATTLLNTYFASLKAKGLKYAYFDKPHTYKVNGVLSGVRDLILIGNAKIESSNLANYFINICQTLTEYNGKYN…
A0A3D3M4C6 13-561 None
A0A2D5J7M7 304-781 None
A0A7U4HCC3 49-587 None
A0A7W3SYZ8 134-685 None
A0A149VF24 61-605 None
S6D9W6 199-796 None
S6D435 13-512 None
A0A2S4LJE3 14-455 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.