DPCstruct | MC24663

Metacluster Properties and Pfam Annotations

Number of structural domains142
Mean domain length (aa)152 ± 17 aa
Standard deviation of domain lengths16.56
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score83.88
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)19.37
Pfam Score100.00
Assigned Pfam label(s) PF07884

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E9IYI5 3-143 QLNVGILSMCIIALGLSFYALLVEFKKEHDDSYEAMCDISEHMSCTKAFISEYGKGFGLLPKDSLFNFPNSIYGLACYMLFAILTMY…
A0A7C4N6L2 18-158 SARCCPSNMNRQRIISLLALVGIVVAGYLTYSHYSGEPVYCGGASSWELVNTSRFAFLLGVPVSTLGLAAYVVILILSLIKSDERRQ…
L1K2D5 941-1088 None
A0A2V5XI77 17-169 None
Q5P1W1 118-298 None
A0A4P7U8W7 12-182 None
A0A517YWR3 12-191 None
K2B172 5-143 None
A0A258VQL5 1-158 None
A0A2Z4FI83 20-194 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.