DPCstruct | MC2461

Metacluster Properties and Pfam Annotations

Number of structural domains92
Mean domain length (aa)183 ± 42 aa
Standard deviation of domain lengths41.77
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score86.33
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)22.10
Pfam Score84.40
Assigned Pfam label(s) CL0015- PF00643- CL0105- PF04253- CL0229

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A438IHY8 293-459 DPMFHRHAAGVLPFDYLSYAYELQKSAKELEGEISNKGINLIPLFKSIEKFKRAATKINHQRKEIEENKGWASIWKKEHLKVRELND…
A0A834A8T9 23-211 AFDTFDYVDKFVDPGFSSHQAVAQTAGNVLLRLSDSLFLPLNVSDYSETLRSFLQAAQQDLGALLEQHNISLGPLVAAVEKFEGAAV…
A0A135V988 874-1063 None
A0A813TV93 540-723 None
A0A0S7DML0 4-187 None
G0PNK9 11-198 None
H0EGM8 550-814 None
A0A7J0GEZ5 414-585 None
A0A2B4SUH7 93-226 None
A0A6N9F482 6-126 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.