DPCstruct | MC24594

Metacluster Properties and Pfam Annotations

Number of structural domains566
Mean domain length (aa)308 ± 93 aa
Standard deviation of domain lengths92.79
Length coefficient of variation0.30
Mean AlphaFold2 pLDDT confidence score82.34
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)15.14
Pfam Score99.47
Assigned Pfam label(s) CL0322- CL0213- PF00375

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A418B8J5 281-773 None
A0A2E1YF27 100-493 None
A0A7W1BGZ7 199-450 None
Q2HB50 48-400 None
A0A377DQG3 1-298 None
A0A1I8F8T8 238-616 None
A0A7S3LVM2 136-526 None
A0A7X6DQG8 72-455 None
A0A446MKT6 2-198 None
A0A0N4VXL4 2-198 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.