DPCstruct | MC24594

Metacluster Properties and Pfam Annotations

Number of structural domains566
Mean domain length (aa)308 ± 93 aa
Standard deviation of domain lengths92.79
Length coefficient of variation0.30
Mean AlphaFold2 pLDDT confidence score82.34
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)15.14
Pfam Score99.47
Assigned Pfam label(s) CL0322- CL0213- PF00375

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A660RJ91 2-174 SKILARYEYNYTIAGTIFVWVKINSEILSSQIKSLFIALLLIFTIVLAIFRRLIISLTTMIPIGFTALMNFINMTVLHINLEISTSI…
A0A7C1W1Z8 65-318 DSNGIPKDNRDVKQLYDYLLKSEEYRKDAKTILHKNGDDYDATVIRVYTTVSSQSNSNETGKELEILYNELVEDIPSFKDCRVSLTG…
A0A6G3UY39 2-260 None
A0A6G3V360 1-242 None
A0A3M1HWH6 74-333 None
A0A532E860 95-558 None
A0A1Q9TF46 20-283 None
A0A7C1MM54 206-508 None
A0A7V3H3G3 6-187 None
A0A812PAA9 66-350 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.