DPCstruct | MC2458

Metacluster Properties and Pfam Annotations

Number of structural domains1743
Mean domain length (aa)195 ± 42 aa
Standard deviation of domain lengths42.06
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.76
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)19.27
Pfam Score71.07
Assigned Pfam label(s) CL0531- CL0063- CL0099- CL0378- CL0046

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z1G6H7 3-156 None
C5KVX9 255-495 None
A0A560T659 289-492 None
A0A455VAM0 46-219 None
A0A6N2HQJ0 174-397 None
A0A1Y2EJU3 70-316 None
A0A519ULD4 15-161 None
A0A7H8QGJ8 334-554 None
M8ASG6 157-308 None
L8WME9 62-250 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.