DPCstruct | MC2458

Metacluster Properties and Pfam Annotations

Number of structural domains1743
Mean domain length (aa)195 ± 42 aa
Standard deviation of domain lengths42.06
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.76
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)19.27
Pfam Score71.07
Assigned Pfam label(s) CL0531- CL0063- CL0099- CL0378- CL0046

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1H1VSV6 659-867 None
A0A832EAW6 13-344 None
E6F2E3 148-373 None
A0A0J7ZII0 4-99 None
A0A8B6E4Z9 383-604 None
A0A0M3J332 38-205 None
A0A812JGF0 226-427 None
A0A6B1P8Y8 705-906 None
A0A6B1P378 30-217 None
A0A6B1P1Q3 1-114 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.