DPCstruct | MC2458

Metacluster Properties and Pfam Annotations

Number of structural domains1743
Mean domain length (aa)195 ± 42 aa
Standard deviation of domain lengths42.06
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.76
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)19.27
Pfam Score71.07
Assigned Pfam label(s) CL0531- CL0063- CL0099- CL0378- CL0046

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C0V6Y6 19-198 None
D9WV37 26-194 None
A0A7S3RZ89 7-156 None
W4M6V0 320-545 None
A0A833GCY4 4-134 None
A0A3Q7GPX9 324-541 None
B8FWY0 21-123 None
A0A428SKF6 727-961 None
A0A1S3HX69 177-405 None
A0A1I8B9N9 42-244 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.