DPCstruct | MC2458

Metacluster Properties and Pfam Annotations

Number of structural domains1743
Mean domain length (aa)195 ± 42 aa
Standard deviation of domain lengths42.06
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.76
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)19.27
Pfam Score71.07
Assigned Pfam label(s) CL0531- CL0063- CL0099- CL0378- CL0046

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q4QNS0 162-409 None
A0A1H0CF67 26-217 None
A0A6H5L033 58-291 None
A0A7J6NNS4 792-1049 None
A0A251XFI1 4-146 None
A0A5C2CW93 30-215 None
A0A0C2GSC4 13-124 None
A0A2N1UZH3 280-493 None
A0A2G3DEQ3 9-161 None
A0A4D8ZDM8 483-717 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.