DPCstruct | MC2458

Metacluster Properties and Pfam Annotations

Number of structural domains1743
Mean domain length (aa)195 ± 42 aa
Standard deviation of domain lengths42.06
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.76
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)19.27
Pfam Score71.07
Assigned Pfam label(s) CL0531- CL0063- CL0099- CL0378- CL0046

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A535QV51 4-101 VIIRGGENIAPREVEEVLMWHAAVREAAVVGRPDPIYGEQVVAYVAVQGAWSEEMAQELRQYAARRLSPHKVPVDFMALDALPRNQM…
A0A445KPD3 287-465 CYQFVPNGTQCPEDVACVGEVGLFPIYMGATDRLLNADNEEVYFKGMPIYKGKVLRRHGDIIKRTAGGRFIGQGRADDTMNLGGIKT…
A0A521YI95 352-555 None
A0A6G1IUU7 128-311 None
A0A822DS12 5-142 None
H0EVN7 16-220 None
H0ETK7 4-186 None
H0ERV2 85-372 None
H0EMW5 36-178 None
H0EKW9 219-442 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.