DPCstruct | MC24575

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)402 ± 41 aa
Standard deviation of domain lengths40.53
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score88.63
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)18.79
Pfam Score91.67
Assigned Pfam label(s) CL0014- CL0016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G8PHP0 1-416 MKRYRVGYIAMPGFNESELGEMQAVLGCHPLNRSSIIAPSKTPVTGQHGMTLVPNADFQDRTPLDVLVIPDIPEAAQDDPALHAFLT…
A0A4Q1ZT03 2-390 DVILYISEAFNLMDMTVPYDLFRKMDEISVKVVGLTKGMVKSEDGISVQVPYGIEDIHHADLLWVCGGDLHSDLFEDQALHKWLKEM…
A0A1R3JWI4 3-351 None
A0A1B0BL29 2-357 None
A0A834L929 582-1052 None
A0A7V4WKQ8 35-427 None
A0A7J7C9A3 5-443 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.