DPCstruct | MC2457

Metacluster Properties and Pfam Annotations

Number of structural domains5
Mean domain length (aa)127 ± 3 aa
Standard deviation of domain lengths2.87
Length coefficient of variation0.02
Mean AlphaFold2 pLDDT confidence score76.25
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)56.08
Pfam Score100.00
Assigned Pfam label(s) PF13236

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A821FDS9 116-245 RFEHIMDHFRAEDANINKLGHEDHIPGQVRDWNEELQITKELPKKNLPERLIRERAMFKVHTDFISAAIRGCQAVVDGNIMAINPGE…
A0A1B0D8T6 198-323 QQEHTIDAIRAEDTFSSKLGYEEHIPGQTRDWNEEIQTTRELPRKNLPERLLRERAIFKVHSDFVTAATRGAMAVIDGNVMAINPGE…
A0A3P8FRY2 70-192 None
A0A077ZMX6 27-153 None
A0A2A2J5U4 85-215 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.