DPCstruct | MC24568

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)135 ± 17 aa
Standard deviation of domain lengths16.52
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score91.66
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)30.39
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2S8VSE3 13-154 TALSHDDRNKVASVHVYRSWLVHPRNITVDLIAIDGAATIDLTRALFQTAEALKDRKFGQVVLARQGKPVFIMEGPAFVELGQQYAA…
A0A5B8LGZ4 3-137 ALSGEKHLTVAYRRWLISPNDIVFDVWRLAPDGSMADMDRQLFKAAEALKGRPFDHVVLAYHGVGRFMIDGAHFGVIGDSWSYQNPI…
A0A7X3P712 2-113 None
A0A1N6EID2 35-180 None
A0A142WTA0 187-313 None
A0A2N3DH46 43-189 None
A0A257YNC2 2-98 None
A0A5C4R4F0 10-144 None
A0A081C9G9 222-383 None
A0A4P5W9R3 26-155 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.