DPCstruct | MC24567

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)143 ± 22 aa
Standard deviation of domain lengths21.79
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score77.08
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)34.02
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A225VWV2 4-142 EVVPASFPQSAVHQPSDHTFFVGIPAWSQHLADDRYTRDGYGRLKVVQCVDGLTAVDLQDLAALIDQGSDVEALTLRPRSDRPLDIA…
A0A6A3WEW9 2-123 SFIVGVPANSSDRLTERFMRDGYGGLEALSFAETLSDEDIQDLSEMVNPRLSIRPNFLLPKSIDATATAPEFRGLLNSMGAKRELAS…
A0A225WC76 51-168 None
A0A6A4DRB9 173-300 None
A0A080YXN5 11-192 None
A0A6G0S121 39-179 None
A0A6G0RL11 81-213 None
A0A6G0RFZ4 216-355 None
H3HAK1 148-291 None
A0A329RT40 3-141 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.