DPCstruct | MC2456

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)99 ± 10 aa
Standard deviation of domain lengths9.77
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score73.31
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)33.29
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J7NLI3 3-85 SRWPKRRLEYAAEVIVEALKELQGGMSRQEVKDAARLHIGDTGLLDFVIKSINNYIIGNYMVLRTLIPSTRVLEININDVNSP
A0A445KAG8 68-167 KQSSSKSKRKKHDSRDRWSAERYQLAEQNMWEVLKAEGATFENPITRPALRLAARKHIGDTGLLDHLLKHIDGKVAPGGTERFRRWF…
A0A2G5DU39 166-263 None
A0A4P1R8C1 875-969 None
A0A6D2I5Q8 117-214 None
A0A6D2I636 190-282 None
I1HUC5 372-462 None
A0A2P2MM24 335-440 None
A0A2P6RSB1 246-344 None
A0A5N5IVA5 2-126 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.