DPCstruct | MC24558

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)167 ± 17 aa
Standard deviation of domain lengths16.82
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score81.73
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)36.27
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A225VI05 13-187 WTTTTPYRAVAWTFVCEVWRVLCLNCSMAAEIVAKYQEVVQDQTIQQIRGWAYVGALGGAALSVPTLVLSANEERYGRYGRMHCARW…
A0A225VBH6 2-181 VWVLTTLFRLVAWTFTQQVWWVVRMNVGMCFEFIARYQDVLRSPELQQLSGPSYAYALWSVLFTVPVELLAEFDDDYGRYGRMVRSW…
W2YKK8 18-183 None
A0A6G0R3E2 35-193 None
A0A080ZKK8 1-149 None
A0A6A3JD96 2-155 None
A0A329RU31 10-189 None
A0A225UZU9 5-184 None
A0A6A4B3R9 34-193 None
A0A6A3N000 61-243 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.