DPCstruct | MC24556

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)254 ± 42 aa
Standard deviation of domain lengths42.21
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score73.80
Mean fraction of residues predicted as intrinsically disordered0.44
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)30.65
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A225V4Z1 4-292 RLAFFLWGLNVPLEGRVAQAARRRKKSDAIAGRTEFVSFMIETWGWYGTLHRVEKSGHRQTFWWGGQPGRNQPSSEYKGPKIMDLGV…
A0A225UZJ0 63-293 REIFWRSIFQVPLDDTQAATNRRHDKYKANAARILFFSLCVETFGWFEFLRRVEKNHSLCWMGGTPGFGTREAKTLIEGLPSEDLVA…
A0A329RKJ3 39-207 None
W2G5Q4 5-234 None
W2XXI1 1-218 None
W2M3E9 1-253 None
W2PRM2 73-386 None
A0A6A3UZG6 2-244 None
A0A6A3ZHL6 135-345 None
A0A6A3HHQ9 135-412 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.