DPCstruct | MC24540

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)115 ± 15 aa
Standard deviation of domain lengths14.55
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score86.83
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)30.75
Pfam Score100.00
Assigned Pfam label(s) PF12270

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q6AE85 6-103 EWVGTVALALSAILAAFLAFYIGRSHASQGGELPEDRLDANIDDGDPELGHFSPWSWWPVALASAAALVLLGLAVGFWLCFIGVAFA…
A0A0M8UI63 2-114 FFGATTAVYWWFSREPAGTAALCVSFVMASLVAAYLWRQYRRGGARPEDRGGAEIREAGGRRGFFPARSHFPALTAAGTALIGLGVV…
A0A538DDB9 20-141 None
A0A0X3VQW2 14-126 None
A0A3L6ZPK3 14-137 None
A0A399XTY9 66-187 None
A0A3D3YVN0 1-127 None
A0A3C1CM33 37-168 None
A0A7W0QH74 246-371 None
A0A6J4HLZ0 13-133 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.