DPCstruct | MC24525

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)135 ± 24 aa
Standard deviation of domain lengths23.61
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score89.82
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)42.52
Pfam Score85.12
Assigned Pfam label(s) PF00631- CL0272- PF18148

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4VHT2 1-119 MRARSKVSQAAECLVASYETYLEFDPLLSPVLPSNPWLTDDPTFMELGQPLVECPTEWRVRRWAISLDELAADPTGLHEITKCMQKE…
A0A671UI27 142-267 IFYQQAIMRSKVKSSVSLGALVKYVTTYKNHDPFLAPCLPSNPWQTDNDTYWNLNMRRVEVPTKSRVERWSFSFFELLSDLRGRDDF…
A0A3P7JD52 52-197 None
A0A7I1A6S0 349-465 None
A0A6P4JZY1 384-544 None
A0A7R9E980 19-164 None
A0A5E4Q4M0 35-192 None
A0A4Z2G1A7 90-191 None
A0A7J7AXA2 47-206 None
A0A3Q3IVF8 211-337 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.