DPCstruct | MC24524

Metacluster Properties and Pfam Annotations

Number of structural domains544
Mean domain length (aa)170 ± 30 aa
Standard deviation of domain lengths30.47
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)12.14
Pfam Score95.89
Assigned Pfam label(s) CL0116- CL0080- CL0456- CL0172- PF10504

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5E4PR31 28-143 None
A0A6P7DZ41 3-244 None
B5M7B6 3-125 None
A0A2Y9FPY9 6-119 None
A0A1Q9CK01 61-269 None
A0A6M2E8E8 99-245 None
A0A6M2E998 48-166 None
A0A821U2V4 4-200 None
A0A0C9SFB7 8-182 None
A0A821U561 121-347 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.