DPCstruct | MC24524

Metacluster Properties and Pfam Annotations

Number of structural domains544
Mean domain length (aa)170 ± 30 aa
Standard deviation of domain lengths30.47
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)12.14
Pfam Score95.89
Assigned Pfam label(s) CL0116- CL0080- CL0456- CL0172- PF10504

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0B2VKH7 81-275 None
D7FWG8 123-320 None
A0A521YHT1 47-225 None
G1L9G3 15-192 None
R1D9D5 87-236 None
A0A1U7T455 3-197 None
G1S4D2 2-155 None
L1IE14 42-189 None
A0A0K8R7W3 33-192 None
A0A131YSD4 13-192 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.