DPCstruct | MC24524

Metacluster Properties and Pfam Annotations

Number of structural domains544
Mean domain length (aa)170 ± 30 aa
Standard deviation of domain lengths30.47
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)12.14
Pfam Score95.89
Assigned Pfam label(s) CL0116- CL0080- CL0456- CL0172- PF10504

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2E1NC39 5-148 EFVDLERFMGDWYVIANIPTFIEKRATNAIESYELMEDGKTIKTTFSFFNDSPDGKKKVYNPTGFVYNSETNAEWRMQFIWPFKSVF…
A0A8B6E124 16-181 SLATCQVPRWGSCPDIPVKQNFDADRYLGKWYENEKFFFIAEIGLKCISANYSLNNDGSIKVLNAGINTRTGRPSEAVGRATIGEKE…
E9FY93 2-146 None
A0A7E4VJU0 4-171 None
A0A417DF35 44-293 None
A0A1D2N414 32-180 None
A0A182FKT6 118-323 None
A0A1X6PG02 209-400 None
A0A834Y2I5 3-151 None
A0A834Y487 22-192 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.