DPCstruct | MC24513

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)129 ± 11 aa
Standard deviation of domain lengths10.79
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score83.82
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.90
Mean intra-cluster sequence similarity (%)44.95
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D4JJA5 221-354 INQLVLHEEDKLKVFDKNSPYLATKKIGKNNPMEEQIKADNEVRQEWNRTVDRAIVSGVSEEDISRIKKNEITEKVRYSIDLYGDRP…
A0A3A8WEV6 101-215 FTAFINTFVFDEKKKLAVFDKHSPYLTTKKIGKNNPREEQIKTDNWARTEWNRTVDRTLVEGISREEVLQVKREEITEKVQESVHKW…
K1UQ76 58-169 None
A0A4S2HJZ3 19-130 None
A0A1C6IY49 2-137 None
A0A0J1G0L6 1-129 None
A0A373IQI9 134-272 None
A0A7X7RR87 104-238 None
A0A0J8YYD4 65-205 None
A0A7X5D528 70-204 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.