DPCstruct | MC2451

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)129 ± 20 aa
Standard deviation of domain lengths19.57
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score73.97
Mean fraction of residues predicted as intrinsically disordered0.48
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)44.26
Pfam Score98.44
Assigned Pfam label(s) CL0123- CL0014

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0L1KZQ0 6-119 KNRDEILMELFTDGVMVCKKEFGKHLKLNVSNLEVINLMRSFKAKKYVDEVYVWHHFYWTLTEAGIEYIRKLLYIKPNIVPNTMKAG…
T0MJP2 1-85 MSLTIAQKIKVYKHFSEKGALLIFDKQHESNKILNINNKKLRSFIQSLKDRGYVKEYYVWQQAYILATNSGMEFFDEETRIPDKL
A0A3P6EKM5 53-159 None
A0A4U0V661 11-154 None
A0A7R9KG05 132-273 None
A0A5J5CV24 5-160 None
A0A0H5BKK1 1-83 None
A0A4Q2DMH7 292-433 None
A0A1S3EF67 344-492 None
A0A2C9VT66 1-145 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.