DPCstruct | MC24508

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)349 ± 79 aa
Standard deviation of domain lengths78.94
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score73.80
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)33.20
Pfam Score100.00
Assigned Pfam label(s) PF08118

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3L6P891 1-306 MEDLLLTVHQPGGFRPFSISIFSCELPQLRKQWLFYDFLSANHMSGSYDGSLFTIHPRQVHGVVPSGNGDPEASVGFGDPKAWKKFS…
A0A2H3IRY6 49-407 QFDVSIDTVNVTLSFTKWFNGKGLLRDVEVKGIRGVIDRTHVHWTDYNADPKSYRHEHNPGDFEIDSFKMEDLLVTVYQPNNFRPFA…
A0A0E9NMH0 358-713 None
A0A098VUL1 76-474 None
M5G2G0 474-843 None
R1GWS4 1-216 None
A0A0C2YWI5 72-365 None
A0A0F7S270 696-1146 None
A0A4T0EWP6 177-517 None
H0EXF3 2-233 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.