DPCstruct | MC2450

Metacluster Properties and Pfam Annotations

Number of structural domains142
Mean domain length (aa)216 ± 53 aa
Standard deviation of domain lengths53.15
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score78.90
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)23.46
Pfam Score99.32
Assigned Pfam label(s) PF00956- CL0071

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
F9G0G8 20-227 None
V4T461 10-168 None
A0A2K5E6A1 2-190 None
A0A4W2BNT4 47-222 None
B0W4W0 12-180 None
A0A6A2WHG5 177-409 None
A0A5N6SNR7 13-244 None
A0A016VZN9 7-183 None
A0A835ZT84 69-267 None
A0A818SSG2 5-217 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.