DPCstruct | MC2450

Metacluster Properties and Pfam Annotations

Number of structural domains142
Mean domain length (aa)216 ± 53 aa
Standard deviation of domain lengths53.15
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score78.90
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)23.46
Pfam Score99.32
Assigned Pfam label(s) PF00956- CL0071

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0L1KS02 24-248 LPVEVRCRTYALMSVGKQLSAVKDAHLSNVFKLQKDNEELLRKLYEERRKVVDPNGGLGGVPGFWLNCLLKNETTAPMISSRDKEAL…
G8JML1 6-179 EVTASALQALSELEDEMEAVELELEKQRKVLLAPVYKKRSAVIEGIEGFWRIVLTQHGEFANYIRACDFRYVEAIRRVEVEWRWTER…
M2Q344 15-235 None
H0EIX9 6-235 None
A0A2P6RY58 5-170 None
A0A4Y7JS83 23-251 None
A0A022R1L5 22-177 None
A0A5N4A6W3 15-169 None
A0A504X645 36-298 None
A0A2P5FEC0 16-181 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.