DPCstruct | MC2449

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)85 ± 7 aa
Standard deviation of domain lengths7.20
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score87.19
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)58.37
Pfam Score100.00
Assigned Pfam label(s) CL0194

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A397GY52 195-280 MPINRIWDHYEIAKQGYSTESAKHMHEVTEYCIIDALRCQQLLVKRNVINDNREVASIAYVSLFDAHYRANGMKVCNLLGAEAWKQ
A0A372RKA4 192-274 KSISTLWKYYSEARDGTSDSSIKNMQEIAKYCVIDALHCQELMVKNNIINDYREVASIVYISLFDTHYYAIGIKVSNLLGAEA
A0A2Z6Q9C4 442-523 None
A0A2N0S7W1 1-82 None
A0A2N0S0P9 1-77 None
A0A397IXS1 2-82 None
A0A2H5S770 257-342 None
A0A2Z6RLX4 141-226 None
A0A2I1FF19 1-83 None
A0A372QNI6 275-355 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.