DPCstruct | MC24488

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)140 ± 10 aa
Standard deviation of domain lengths10.29
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score86.33
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)33.44
Pfam Score100.00
Assigned Pfam label(s) PF01295

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A109LIU4 240-390 MTEFELFNLLGSLQQTITLPLASVDEVRLLRPAVPEEVLLLINVGIDPLKHHRDLNILMTTERTDSLSYAGVRDNLVLTLDQVTLNS…
A0A1V5ED05 1-128 MLPNATSITLQEIVNLGRKVRDFFGISDIAAVEFPNYLEDERIQKALIVVNFETAGYGKEIRDLRLIFRNNRGELFVRRWGSPEALK…
A0A6I4KMG4 291-439 None
A0A7V5HA50 108-256 None
A0A355B1N9 626-767 None
A0A6M1HV82 2-120 None
A0A2X1PHN5 1-149 None
A0A090PMH9 89-237 None
A0A6L2ZQ34 520-668 None
A0A376YK75 4-140 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.