DPCstruct | MC24469

Metacluster Properties and Pfam Annotations

Number of structural domains48
Mean domain length (aa)241 ± 48 aa
Standard deviation of domain lengths48.13
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.54
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)13.43
Pfam Score64.44
Assigned Pfam label(s) PF04245- PF14199

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T0CN25 1-176 MIIHKFIVHVLDKNSEVPILNDFEGKVSQEVDKFFQKIIKRVSKDDDLRKGIFKDYENNVVKNCCEQIIYDESTFLENSKEIAAYLF…
A0A395TJP7 22-236 IKKLYVYDIDVSQKIPTHVTQSEQMSDLGSFLLRVSQETMTSPNKKLYEFEPTSSAQTCIKEFLTATTQAEEEISSMNLAKLLLDAE…
A0A7C9TRP3 1-189 None
A0A6N6X733 1-162 None
A0A0C5XUU0 2-193 None
R7QZL6 1-260 None
A0A352NVG8 4-237 None
A0A7X5RJV8 2-167 None
V9W7T6 1-205 None
A0A3D4JLE4 1-270 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.