DPCstruct | MC24468

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)104 ± 7 aa
Standard deviation of domain lengths6.57
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score92.73
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)26.96
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y1ZJI8 136-237 DDLGDRGGTLQFLQQYIAEQGAATVMTAVVYMKPQAMELCPADFYFGEVAQDCWIITPREAVETLVKRVPVWRERGADVAECRRRLV…
X1GVU4 16-126 IFFLTDKSSKLTKRILEYSEEAYLQMAAIDHIKEMGAKEIRTSTLYYKKHSVIKPEYYIKETKAWIVYPWEYGEFAAFQYDQLKEKM…
G9EUJ3 4-105 None
A0A2J4G6Q5 73-185 None
A0A7J3BDK8 73-170 None
A0A645HSQ8 2-101 None
A0A7C0XH22 46-148 None
A0A7J3JBA2 194-288 None
A0A2D6V4P6 178-268 None
A0A843I824 39-151 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.