DPCstruct | MC24444

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)93 ± 5 aa
Standard deviation of domain lengths5.32
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score90.69
Mean fraction of residues predicted as intrinsically disordered0.55
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)42.71
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5N7AJK2 886-989 TWGGGGLGDPLTRPAEKVALEIRRRLVTVDGARNNYGVVVNPDDLSVCEEETVALRKSMKEARDALGQTPEYDRGGSMEELRESCLR…
A0A0S6X5M2 1-89 DRDPALVLTEIGQGLVTETGALDYGVVIKDGAVDETATQALREKMRTERGEVEVFNFGPDIETLRKNCLEETGLPAPKQPMWRTAEA…
A0A6S6Y2V7 115-203 None
A0A3M7AQI4 201-297 None
A0A7C3C1E0 206-291 None
A0A146IN89 324-415 None
A0A0N8KHN3 22-111 None
A0A3F3R8Y1 177-269 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.