DPCstruct | MC24434

Metacluster Properties and Pfam Annotations

Number of structural domains61
Mean domain length (aa)133 ± 23 aa
Standard deviation of domain lengths22.65
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score87.31
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)35.78
Pfam Score95.85
Assigned Pfam label(s) CL0179- CL0021

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C3UEB7 6-91 PRGMIAYKFPPEEATTIVEDITVQVGRTGALTPVAVLKPVLVAGSTISRATLHNEDEIKRKDIRIGDTVVVRKAGDVIPEVASVLK
A0A350I8F3 206-298 VYRLNSRDKFDRMGYTAHHPRGSVALKEQKEGQITTLLDVVWQVGKSGVVSPVAILDPVDIEGAIVSRATLHNIDYIRSLDLKIGCN…
A0A837Q3Q1 22-175 None
A0A1X6PJS6 531-677 None
A0A835XV96 680-809 None
W3Z9Y8 1-67 None
A0A7V4UW92 18-149 None
A0A0K2QZV3 6-145 None
A0A485AQA7 56-182 None
A0A1E4ZIW4 273-412 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.