DPCstruct | MC24429

Metacluster Properties and Pfam Annotations

Number of structural domains145
Mean domain length (aa)110 ± 14 aa
Standard deviation of domain lengths13.98
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score86.61
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)27.21
Pfam Score97.08
Assigned Pfam label(s) CL0123- CL0603- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5D2TBN9 69-186 KVIDGKSVAKQIREEISAEVTKLKEAIGVVPGLAVILVGDRKDSATYVRNKKKACESVGIKSFEVNLPNDASEQEVLKYISDFNGDP…
A0A412AWW1 410-525 IIDGKAVSAAVRAGAKQEVEALKAQGIQPGLAVVIVGDDPASRVYVNNKKKACAEIGIHSEEYALPKETTQEELLDLVCRLNDKKDI…
A0A5A9NF52 370-496 None
A0A365N406 21-127 None
A0A0D2MUA5 8-96 None
A0A4U0VQE3 513-634 None
A0A553MV03 16-134 None
A0A182U3I7 3-100 None
M9LXY8 531-653 None
A0A6J0NHZ3 63-170 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.