DPCstruct | MC24400

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)346 ± 47 aa
Standard deviation of domain lengths46.56
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score91.34
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)29.63
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y1IQJ7 117-453 FDPPGFVDDLTSAAEKRGWSDWISRQMDRAVKGTPSRNDGPRRQFLNPSKPSTPLVEPVTYKDISWTAFPRQVDVDTGSDSARWAAA…
A0A4V2LDU2 14-320 DAPRPRFFNVAKTPLAADAVEKDISWTAFPRLVAIDAATDEERWKTADGSRDVQDEYCEWSVTRLADGRISRVTFTCEGPEYWQFLA…
A0A7W0FXS0 189-549 None
V7GVR5 3-360 None
F8CM33 5-379 None
A4YMN2 77-449 None
A0A2Z6RDG1 759-1103 None
A0A6P0MCF5 21-324 None
A0A7Z0QLY2 3-358 None
A0A175WG83 19-334 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.