DPCstruct | MC24373

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)258 ± 29 aa
Standard deviation of domain lengths29.23
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score79.28
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)18.02
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y7PUE7 60-331 SLSAEKPTGEWALKAIDKWKLQPPYDTAITEALWQEYYETRIKIKVPGGSYLYGEEIKQFDEEKIGKKNRKSPVYKALVLAREQMSV…
A0A812GET3 20-282 TVMPGKFDLDITNVTGHWDPSVLEEEWKAWYDLRKQAESHCSQLLREGCEGEGDEEKDEEEEFDVDDHDEDYYQSSRFQLKMLKDLR…
A0A0K6FW40 348-638 None
A0A2H3D4Y4 4-247 None
A0A1B7MP43 22-302 None
A0A0B7FB92 3-266 None
A0A0D7API7 36-352 None
J0WZA6 2-234 None
A0A5M3MC07 47-330 None
K0R8K5 13-289 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.