DPCstruct | MC24354

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)122 ± 20 aa
Standard deviation of domain lengths20.18
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score80.74
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)27.81
Pfam Score83.33
Assigned Pfam label(s) CL0014- CL0382

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0X3BP16 39-144 PSPVIKRMMWGSLSTDMLQTYGHLVDKDIDAAIAQLYGVVTPETETSDSLEPRQCPRCLSVWGPALQHCGVCGAPLTREGMADLDDA…
E7QNG8 118-275 ERMSYVTFQRYFKRAAKRIGLDKPVTPKNFRKSNATWLAKLGKNESFIEDRQGRKRGSDAISHYVAMYGEDRAREYAAMHGQDVETE…
A0A832RVQ5 1-88 None
A0A7C4GTB4 18-134 None
M0HU60 57-179 None
A0A3R7EDY9 429-542 None
T0M9R1 157-274 None
A0A7K4B8R0 1-78 None
A0A7J4LMM2 47-184 None
A0A848E654 192-305 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.