DPCstruct | MC24353

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)92 ± 6 aa
Standard deviation of domain lengths5.64
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score97.19
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.97
Mean intra-cluster local Distance Difference Test score0.92
Mean intra-cluster sequence similarity (%)62.63
Pfam Score100.00
Assigned Pfam label(s) CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376SZU1 45-137 LRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAW…
A0A1V3WPI7 169-262 LLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTHFDELCDIFARYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELTKIA…
A0A2R7QBU0 320-412 None
A8FKN8 164-260 None
A0A1B0C474 337-431 None
A0A7C3ZFD7 162-241 None
A0A379W0F0 343-425 None
A0A0B8PDZ4 57-149 None
A0A4Y6UBA1 273-366 None
A0A800CXV0 91-173 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.