DPCstruct | MC24331

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)83 ± 9 aa
Standard deviation of domain lengths8.52
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score85.76
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)42.07
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Q7TQC1 2-69 LRRLDQFREWHSLDDKRFCLVCGKIIVGGQIQINGGTRGNGPLRLSCPTERCNSIPMDWVLPTDELVA
A0A538NWC6 11-95 AMALVSPNKLSDEEKLETLQRLDQFRQWHSLDEKRYCLVCGKIITGREIQVIWGTRGNGPLRIVCSTERCNAIPMDWVRPTVEVH
A0A4Q2YRQ3 9-89 None
A0A2V6DVF9 1-76 None
A0A2V6J0M4 2-73 None
A0A2V6ISZ1 4-89 None
A0A2V5ZQB9 52-140 None
A0A2V5XKM7 3-84 None
A0A2V6EHE8 19-100 None
A0A2V6BYW9 35-125 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.