DPCstruct | MC24325

Metacluster Properties and Pfam Annotations

Number of structural domains107
Mean domain length (aa)169 ± 29 aa
Standard deviation of domain lengths28.66
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score87.30
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)32.38
Pfam Score100.00
Assigned Pfam label(s) PF02538

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A448UPH6 40-212 DPIGYEKMFSKLRGGIVHARETAKRIAASPIVEQEGELCFTLYNAVGDSVLTSTGIIIHVGTMGSAIKYMVENNWEDNPGINDKDIF…
A0A482Y2G9 70-254 RYEQLYARLRGDLVTARETSKEVSATPIVEQEGELCYGLFTPEGDSIAVSTGIIVHVHTMSEAIKFMINHDYEESPGIEPGDIFVNN…
A0A7L9WIY6 2-146 None
A0A0M3IQS7 3-107 None
B8IKP0 7-195 None
A0A849WU36 3-164 None
E7F6Z6 741-913 None
A0A2K0UQ43 78-202 None
A0A317WHJ4 630-765 None
A0A212DNY4 232-384 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.