DPCstruct | MC24320

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)142 ± 24 aa
Standard deviation of domain lengths23.62
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.43
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)42.73
Pfam Score95.45
Assigned Pfam label(s) PF04560- PF04997

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2X1PMS7 18-157 FDVIKIGLASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMG…
A0A0G0PPX0 5-135 FKSMTDFDGLKIKLASPEEILSWSHGEVTKPETINYRSWRPEKDGLFCEKIFGPTKDYECYCGKYKKIRFKGVICDKCGVEVTTSKV…
A0A3D9JM13 754-873 None
A0A7W0Q724 269-370 None
A0A3R6IGC9 19-153 None
A0A396I204 187-306 None
A0A5D2CU41 7-92 None
A0A381KMK2 3-166 None
A0A7C6Y895 126-296 None
A0A7G0X258 6-153 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.