DPCstruct | MC24315

Metacluster Properties and Pfam Annotations

Number of structural domains291
Mean domain length (aa)78 ± 13 aa
Standard deviation of domain lengths12.53
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score78.20
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)31.26
Pfam Score93.99
Assigned Pfam label(s) PF00095- CL0220- PF09307- CL0620- CL0005

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S4RY98 93-170 None
A0A3Q3VVL6 21-105 None
E4XY41 226-315 None
A0A226P4Q1 1-71 None
A0A7R9DVU3 80-151 None
A0A5C6P3B8 154-261 None
A0A498N3L4 385-463 None
A0A3Q3W242 5-73 None
T2M8U2 274-346 None
A0A6V7X6T0 138-213 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.