DPCstruct | MC24307

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)126 ± 18 aa
Standard deviation of domain lengths18.21
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score87.30
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)48.89
Pfam Score96.43
Assigned Pfam label(s) CL0023- CL0110

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A075FGY6 75-188 VDLNDRALRRININLGGVANGFPREDGFDITVASEIMAIFCLSNNLKDLEEKIGNITVAYTREKKPIYAKDLNAHGPMTVLLKEAIK…
A0A2E8GRQ2 6-126 IGMSIDLENITWRRTIDLCDRQLRNCEVGLGSKFDGFAHKTGFDIVAASEIMTIMALAKDMADLRERIGRIVVAYNRSNKPVFAREL…
A0A0D8XDL0 18-164 None
A0A4W5PLI1 40-140 None
A0A2U1PIV0 157-277 None
A0A5S9ME17 78-193 None
A0A101I5C9 226-389 None
A0A837AU06 169-277 None
A0A1A6H879 212-345 None
A0A060X745 554-667 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.