DPCstruct | MC24293

Metacluster Properties and Pfam Annotations

Number of structural domains47
Mean domain length (aa)117 ± 20 aa
Standard deviation of domain lengths20.49
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score80.41
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)38.33
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R9CX66 20-135 EVGEEYDPTELVCGACSDVSRAQMCPKHGTDFLEYKCRYCCSTAVFFCFGTTHFCNACHDDFQRVTNIPRLELPTCPAGPKAKQLEG…
A0A0K0D294 11-112 LVCGGCSAPPGTDVCGRHGAEYLEYKCRYCCSIAVYFCFGTTHFCAPCHDDFQRLVCLPRSQFPPCPTGPRATPSEGPCPLRRPHPP…
D3AW00 476-580 None
R1D1V4 229-324 None
D3AZM8 500-613 None
A0A4W4FJ93 364-497 None
A0A0V0Q7Z6 509-588 None
F4PV64 993-1106 None
F4PW33 618-736 None
A0A0D8XSF4 818-948 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.