DPCstruct | MC24275

Metacluster Properties and Pfam Annotations

Number of structural domains159
Mean domain length (aa)186 ± 41 aa
Standard deviation of domain lengths40.56
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.05
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)18.37
Pfam Score79.14
Assigned Pfam label(s) CL0020- PF05278- CL0072- CL0389- CL0229

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A2YWH4 190-372 None
A0A5J5BFJ3 612-775 None
A0A5N5EWH5 112-295 None
A0A6P5YBX4 257-469 None
A0A2U1M1V7 232-457 None
A0A061F956 323-548 None
A0A2N9HH12 623-772 None
A0A2N9HQF6 1-155 None
A0A5J5B6S8 615-826 None
A0A6A1VNZ1 92-280 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.