DPCstruct | MC24275

Metacluster Properties and Pfam Annotations

Number of structural domains159
Mean domain length (aa)186 ± 41 aa
Standard deviation of domain lengths40.56
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.05
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)18.37
Pfam Score79.14
Assigned Pfam label(s) CL0020- PF05278- CL0072- CL0389- CL0229

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y7LB34 195-400 None
A0A2P6PL44 760-938 None
A0A5B6VS11 135-289 None
A0A5B6VSG5 36-167 None
A0A5B6VSH2 221-368 None
A0A4U5QMG6 369-640 None
A0A7J0EFV0 388-600 None
A0A4S4ETF5 513-779 None
A0A6D2L7W8 166-322 None
A0A6D2LQ81 99-291 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.