DPCstruct | MC24275

Metacluster Properties and Pfam Annotations

Number of structural domains159
Mean domain length (aa)186 ± 41 aa
Standard deviation of domain lengths40.56
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.05
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)18.37
Pfam Score79.14
Assigned Pfam label(s) CL0020- PF05278- CL0072- CL0389- CL0229

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A445E593 30-212 None
A0A445E5L9 487-675 None
A0A6P5WN45 204-447 None
A0A5D2NL61 15-138 None
A0A397Z648 143-316 None
A0A7J7FV03 556-846 None
A0A1R3GPE5 499-707 None
A0A6D2IPM8 19-174 None
A0A7G2DXS9 1-104 None
V4U723 1020-1244 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.