DPCstruct | MC24261

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)560 ± 95 aa
Standard deviation of domain lengths94.57
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score76.08
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)25.99
Pfam Score93.41
Assigned Pfam label(s) CL0110- PF00173

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A642VAI3 502-1081 GSDYGEESVIPYDCSFEDYEVDSLNREYLDRPTAADYGYDTEAVGQQTLQKLSGRRKLWLVIVKLLTWWIPSPLLSIGGMKRSEVRI…
A0A0C3JAF3 27-383 NPNNVYMLNRGGVFDLTAVAATHQRVFSMVSTKSVLQYGGMASDAIFPVQVSALCNGVSGSVSPWVTLDSANNTDPNAQYHDFRAFT…
J4U549 11-548 None
A0A1Y1YBA2 3-403 None
A0A167CJS4 385-1097 None
J9VNT4 831-1373 None
U9UWN8 1-457 None
K0SH62 204-799 None
A0A015KZG8 279-808 None
A0A5C2SZV5 112-634 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.